S13.1 A randomised controlled trial comparing the Maudsley Model of Anorexia Treatment with specialist supportive clinical management in adults with anorexia nervosa
Schmidt, U.
Voorzitter(s): H.W. Hoek
Locatie(s): Auditorium 2
Categorie(ën):
BACKGROUND
Anorexia nervosa (AN) is a severe mental disorder which in adults has an unsatisfactory treatment response with only about 30% recovering with best available psychotherapies. One key factor responsible for the relative lack of efficacy is that treatments for adults with AN have been adapted from those for other disorders rather than tailored to the needs of people with AN or focused on how the disorder is maintained. To remedy this problem we have developed a specific maintenance model and treatment of AN, the Maudsley Model of Treatment of Adults with AN (MANTRA). Our treatment model is novel in several respects: (a) it is biologically informed and trait-focused, drawing on motivational, neuropsychological, social cognitive and personality trait research in AN; (b) it includes both intra- and interpersonal maintaining factors and strategies to address these; and (c) it is modularized with a hierarchy of procedures, tailored to the need of the individual.
Aims: To evaluate the efficacy and acceptability of MANTRA compared to Specialist Supportive Clinical Management (SSCM) in a randomised controlled trial (RCT).
METHODS
142 adult outpatients with AN or eating disorder (ED) Not Otherwise Specified (EDNOS-AN) were recruited from 4 specialist ED services in the UK. Participants were randomly allocated to 20 once weekly sessions of MANTRA or SSCM and optional additional sessions depending on severity and clinical need. The primary outcomes were body mass index, weight and Global Score on the Eating Disorders Examination, at end of treatment (6 months) and follow-up (12 months). Secondary outcomes included: (a) depression, anxiety and clinical impairment; (b) neuropsychological outcomes, (c) recovery rates and (d) additional service utilization.
RESULTS
6-and 12 months outcomes will be presented.
CONCLUSIONS
Findings and their implications for the field will be discussed.